Searchable abstracts of presentations at key conferences in endocrinology

ea0022p109 | Bone/Calcium | ECE2010

Primary hyperparathyroidism at pregnancy

Yorulmaz Goknur , Kebapci Nur , Onbasi Kevser , Efe Belgin , Akalin Aysen

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...

ea0020p303 | Clinical case reports and clinical reports | ECE2009

Large intrathoracic goiter mimicking lung cancer

Onbasi Kevser , Akalin Aysen , Yorulmaz Goknur , Kebapci Nur , Efe Belgin

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

ea0014oc12.6 | Diabetes | ECE2007

Short-term effects of atorvastatin on endothelial functions and oxidized LDL levels in type 2 diabetic patients

Akalin Aysen , Temiz Gokhan , Akcar Nevbahar , Sensoy Banu

Objective: We aimed to investigate the short term effects of atorvastatin on endothelial function and oxidized LDL (oxLDL) levels and to evaluate the association of endothelial dysfunction to oxLDL levels and inflammatory markers in type 2 diabetic patients.Material and methods: After ethical committee approval thirty type 2 diabetic and 11 healthy subjects with LDL levels between 100–160 mg/dl. Without a history of cardiovascular event were include...

ea0011p82 | Clinical case reports | ECE2006

A case of primary pigmented micronodular hyperplasia as a cause of Cushing syndrome

Akalin A , Son O , Isiksoy S , Kebapci N , Efe B

ACTH-independent micronodular adrenocortical hyperplasia is a rare cause of Cushing syndrome. In some forms of micronodular adrenal disease, darkly pigmented micronodules are seen in the presence of atrophy of the peripheral adrenal tissue. In most cases of pigmented micronodular hyperplasia Carney complex is associated with the disease. Here, we present a case of Cushing syndrome due to sporadic primary pigmented micronodular hyperplasia not accompanied by Carney complex....

ea0007p51 | Diabetes, metabolism and cardiovascular | BES2004

Relation of plasma homocysteine levels to atherosclerotic vascular disease and inflammation markers in type 2 diabetic patients

Akalin A , Alatas O , Colak O , Sahin F , Efe B

Both hyperhomocysteinemia and increased inflammatory activity are shown to be associated with atherosclerosis. But, the relation of inflammatory activity to homocysteine levels is not well established. In the present study, we aimed to evaluate the relation of plasma homocysteine (tHcy) levels to atherosclerotic vascular disease and inflammatory activity in type 2 diabetic patients.Ninty type 2 diabetic patients were included in the study. Forty one of t...

ea0081ep722 | Pituitary and Neuroendocrinology | ECE2022

Assessment of the thyroid status in acromegaly patients

Yuksel Bahar Gokce Sezgin , Yorulmaz Goknur , Kalkan Ahmet Toygar , Kebapci Medine Nur , Akalin Aysen , Efe Belgin

Acromegaly is a rare disease associated with hypersecretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland, with elevated morbidity and mortality. Acromegaly and thyroid diseases show high co-occurrence. In our study; we aimed to determine the relationship between disease activity at the time of admission and after treatment with the presence of goiter, presence of nodules, and possible accompanying thyroid malignancy in 119 patients with acromega...

ea0090p810 | Late-Breaking | ECE2023

Evaluation with Dynamic Contrast Enhancement (DCE)-MRI in Patients with Acromegaly

Toygar Kalkan Ahmet , Ozer Ozge , Toprak Ugur , Efe Belgin , Akalin Aysen , Nur Kebapci Medine , Yorulmaz Goknur

Acromegaly is a rare disease with high morbidity and mortality associated with excessive secretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland. In patients with acromegaly, residue may remain after surgical treatment, and disease control is attempted with surgery, medical treatment or radiotherapy for these patients. Pituitary imaging, IGF-1 and GH measurement are used in the follow-ups. Dynamic Contrast Enhancement perfusion MRI provides infor...

ea0037ep941 | Thyroid (non-cancer) | ECE2015

Ultrasonography-guided fine-needle aspiration biopsies of thyroid nodules: single-centre experience

Susuz Salim , Kebapci Nur , Kasapoglu Emine Dundar , Kebapci Mahmut , Cevikalp Ozge , Efe Belgin , Akalin Aysen

In the present study, we aimed to investigate the efficiency of ultrasound-guided fine-needle aspiration biopsy in our clinic. Totally, 701 patients followed at Department of Endocrinology, Faculty of Medicine, Eskisehir Osmangazi University with nodular thyroid disorder were included in this study during January 2000 and January 2011. Ultrasound-guided thyroid fine-needle aspiration biopsy was performed in these 701 cases at Interventional Radiology Department. Throid nodules...

ea0070ep289 | Pituitary and Neuroendocrinology | ECE2020

Clinical and endocrinological evaluation of patients with empty sella

Nur Kebapci Medine , Kesebi Isganderov Duygu , Yorulmaz Goknur , Akalin Aysen , Efe Belgin

Empty sella (ES) is characterized by herniation of the subarachnoid space within the sella, compression and flattening of the pituitary gland. Stretching of the pituitary stalk may also be seen. Empty sella is a frequent finding (5–23%) in autopsy series while it is < 0.01% in persons who undergo medical attention. Meanwhile there is an increase in sellar emptiness with age. Regarding pathophysiology and etiology, it may be primary to the incompetence of the diaphrag...

ea0022p147 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Gender variations of serum Paraoxonase-1 activities in healthy young men and women: association with carotid intimae media thickness

Yavuz Dilek Gogas , Tarcin Ozlem , Gun Palmet , Sirikci Onder , Akalin Sema

Aim: Paraoxonase-1 (PON-1), an HDL-associated enzyme has been shown to possess antioxidant properties that protect against atherosclerosis. The aim of this study is to evaluate serum paraoxanase activities, lipid profiles and carotid intimae media thickness (CIMT) as an early marker of atherosclerosis in healthy man and women.Method: Four hundred healthy volunteers (F/M: 250/150, 19–23 years) included in the study. Serum paraoxonase and arylesterase...